Drug X is an investigational agent for high blood pressure. Which of the following study designs would be appropriate for a first in human (FIH) Phase 1 study?

1.
Question 1
Drug X is an investigational agent for high blood pressure. Which of the following study designs would be appropriate for a first in human (FIH) Phase 1 study?

1 point

A placebo-controlled, single dose in healthy adults

An open-label, single dose in patients with high blood pressure

A placebo-controlled, multiple dose in healthy adults

An open-label, multiple-dose in patients with high blood pressure